The Infectious Diseases Research Laboratory (Gal-Mor Lab)

The Infectious Diseases Research Laboratory (Gal-Mor lab) is located at the vibrant Sheba Medical Center Campus in Tel-Hashomer and affiliated with the Faculty of Medical & Health Sciences, Tel Aviv University.

Research Focus

Our research addresses fundamental questions in the microbiology and infectious diseases fields, while using the bacterial pathogen Salmonella enterica as a useful and highly relevant model. Our overall goals are to better understand, on the mechanistic level, how pathogens cause diseases and develop creative novel approaches to deal with burning clinical challenges, such as the antibiotic resistance pandemic and bacterial outbreaks.

Latest Research Publications

Persistent Salmonella infections in humans are
associated with mutations in the BarA/SirA
regulatory pathway

Grote et al. show that adaptations in global regulatory genes arise during persistent Salmonella infections in humans. These adaptations lead to decreased virulence gene expression, attenuated pathogenicity, and a weaker immune response in an acute salmonellosis model but to long-term colonization and shedding in a persistent mouse model